Timothy Ray Brown, additionally known as “the Berlin patient,” was 54.

Brown was thought of cured of his HIV an infection in 2008. In the 12 months prior, Brown acquired a bone marrow transplant in Berlin, Germany, to deal with a separate illness he had been identified with: acute myeloid leukemia (AML).

The bone marrow he acquired got here from a donor whose genes carried a uncommon mutation that made the donor naturally resistant to HIV, known as CCR5-delta 32, which was transferred on to Brown.

Brown remained HIV free — however for the previous six months he had been dwelling with a recurrence of the leukemia that had entered his backbone and mind, in accordance to the International AIDS Society (IAS).

“On behalf of all its members and the Governing Council, the IAS sends its condolences to Timothy’s partner, Tim, and his family and friends,” Adeeba Kamarulzaman, president of the International AIDS Society and professor of medication and infectious illnesses on the University of Malaya, mentioned within the IAS announcement on Wednesday.

Worldwide, there are 38 million people presently dwelling with HIV or AIDS, in accordance to the Joint United Nations Programme on HIV/AIDS.

“We owe Timothy and his doctor, Gero Hütter, a great deal of gratitude for opening the door for scientists to explore the concept that a cure for HIV is possible,” the IAS assertion mentioned.

Brown lived in Berlin from 1993 to 2010 whereas he labored at a restaurant and as a German-English translator, his accomplice Tim wrote in a Facebook post. He was identified with HIV in 1995 and later identified with AML in 2007.

Brown “committed his life’s work to telling his story about his HIV cure and became an ambassador of hope,” his accomplice wrote.

“I am truly blessed that we shared a life together but I’m heartbroken that my hero is now gone,” he mentioned. “Tim was truly the sweetest person in the world. Tim’s spirit will live on and the love and support from family and friends will help me through this most difficult time.”

Over two years in the past, Adam Castillejo — beforehand recognized as “the London patient” — completed HIV antiretroviral remedy, making him the second person ever to be cured of HIV.

Unlike Brown, Castillejo underwent just one stem-cell transplantation as a substitute of two and didn’t have radiotherapy to his complete physique as half of his therapy.

CNN’s Gina Yu and Amy Woodyatt contributed to this report.

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